There are several biological mechanisms that may contribute to the relationship between short sleep duration and diabetes. First, laboratory studies have corroborated decreases in glucose tolerance and insulin sensitivity after sleep restriction2. That is, both inadequate pancreatic insulin secretion and increased circulating glucose levels due to sleep deprivation can lead to the development of insulin resistance and type 2 diabetes.
Second, short sleep duration has been associated with increases in markers of inflammation3, which indicate low-level systemic inflammation and play a role in the development of diabetes4.
It is therefore possible that sleep disruption is related to diabetes due to a low-grade systemic inflammation mechanism.
Finally, short sleep is associated with increased ghrelin hormone (linked to raising appetite) and decreased leptin hormone (associated with reduced appetite), leading to longer feeding times, thus increasing the risk of weight gain and subsequent health risks5.
In this way, faster and more caloric meals are sought, increasing the tendency to obesity, which, as is known, increases insulin resistance, a mechanism directly linked to type 2 diabetes. Obesity is also a factor that increases risk.
So… sleep is vital for a balanced metabolism.















